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Figure 2. Ins and outs of membrane transport proteins in osteoclasts. (A) Schema depicting the major types of transport proteins and their modes of substrate movement across biological membranes. (B) Model summarizing the reported membrane localization of all the major membrane transport proteins expressed in osteoclasts. Known substrates are indicated in gray. Intracellular compartments correspond to: ER, endoplasmic reticulum; SL, Secretory lysosome; LE, Late endosome; TV, Transcytotic vesicle. Created with BioRender.com.

fsd 3 rev 775 318

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